The Tansey Laboratory


We study transcriptional regulation in normal and cancer cells. We are interested in understanding how the oncoprotein transcription factor MYC works, and how it can be targeted for therapeutic effect in cancer cells. We are also interested in how components of the ubiquitin–proteasome system control transcriptional regulators and core components of the transcriptional machinery.



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(all are presumed innocent until proven guilty in a court of law)